Mannose-decorated polymersomes loaded with antigens and TLR7/8 agonists targeting antigen-presenting cells for enhancing vaccine efficacy
Mannose-decorated polymersomes co-encapsulating OVA and the TLR7/8 agonist R848 target mannose-receptor on APCs, promoting enhanced antigen uptake, APC maturation, cross-presentation, and robust cellular and humoral immune responses.
Authors
- Seungjoo Haam (ORCID: https://orcid.org/0000-0002-4990-0523)
- S G Lee
- Jong-Woo Lim (ORCID: https://orcid.org/0000-0002-7953-0914)
- Daesub Song (ORCID: https://orcid.org/0000-0002-2759-1061)
- Minjoo Yeom (ORCID: https://orcid.org/0000-0001-8949-6361)
- Hyojin Park (ORCID: https://orcid.org/0000-0003-4814-8330)
- Sojeong Lee (ORCID: https://orcid.org/0009-0000-4964-0058)
Institutions
- Seoul National University (KR)
- Yonsei University (KR)
Publication Details
- Journal
- Materials Advances
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5ma00115c
- Citations
- 1
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- National Research Foundation
- Korea Research Institute of Bioscience and Biotechnology
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea