Divergent Mono‐ and Di‐trifluoromethylthiolation of Bicyclo[1.1.0]butane and Bicyclo[2.1.0]pentane<sup>†</sup>
Comprehensive Summary Strain‐release ring‐opening trifluoromethylthiolation to construct SCF 3 ‐substituted cyclic motifs was under‐explored, and di‐trifluoromethylthiolation is unachieved. Herein, we present the first trifluoromethylthiolation of bicyclo[1.1.0]butane (BCB) and bicyclo[2.1.0]pentane. By employing different activators, both mono‐ and di‐trifluoromethylthio substituted cyclobutane and cyclopentane derivatives were successfully obtained.
Authors
- Yu‐Xin Luan
- Pingping Tang
- Pengfei Yang (ORCID: https://orcid.org/0000-0003-4346-7367)
- Sihan Chen (ORCID: https://orcid.org/0000-0002-5249-8723)
Institutions
- Nankai University (CN)
Publication Details
- Journal
- Chinese Journal of Chemistry
- Published
- 2025-07-25
- DOI
- https://doi.org/10.1002/cjoc.70194
- Citations
- 1
- Primary Topic
- Fluorine in Organic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.79
Funders
- National Natural Science Foundation of China