Cervical Ectopic Pregnancies—Imaging and Endovascular Treatment

<b>Objective</b>: Cervical pregnancy (CP) accounts for less than 1% of all ectopic pregnancies. The standard of management for CP is still under detailed investigation; however, among the known treatment methods, super-selective uterine artery embolization (UAE) and the use of methotrexate (MTX) have emerged as effective and minimally invasive options in recent years. Our aim is to present our center's experience and provide available evidence evaluating the efficacy of UAE in the treatment of CP. <b>Materials and Methods:</b> This single-center and retrospective study evaluated the procedural and clinical outcomes of patients with CP who underwent endovascular uterine embolization with MTX between 2017 and 2024. Both procedural and clinical efficacy and safety, as well as the rate of complications and long-term outcomes, were noted. <b>Results:</b> A total of nine patients were diagnosed with CP (imaging examination included transvaginal ultrasound and/or magnetic resonance imaging) and referred for endovascular treatment. The mean age of the patients was 36.7 years, and the mean gestational age on admission was 9 weeks. In all cases, selective catheterization of supplying vessels and subsequent embolization with a mixture of methotrexate and gel sponge was carried out. The technical success rate was 100% with no complications. Follow-up ultrasound confirmed the disappearance of the flow signal around the intracervical gestational sac in all cases. <b>Conclusions:</b> In conclusion, this retrospective study demonstrated the procedural and clinical safety and efficacy of uterine artery embolization in patients with cervical pregnancy. This is why endovascular therapy should be proposed to these individuals and be included in treatment options discussed during multidisciplinary boards.

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Publication Details

Journal
Diagnostics
Published
2025-08-04
DOI
https://doi.org/10.3390/diagnostics15151956
Citations
3
Primary Topic
Ectopic Pregnancy Diagnosis and Management
Type
article
Field-Weighted Citation Impact
5.64
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article

Cervical Ectopic Pregnancies—Imaging and Endovascular Treatment

Krzysztof Pyra, Maciej Szmygin, Weronika Dymara-Konopka, Sławomir Woźniak et al.
3 citations
Diagnostics
Ectopic Pregnancy Diagnosis and Management
5.64
article

Cervical Ectopic Pregnancies—Imaging and Endovascular Treatment

Krzysztof Pyra, Maciej Szmygin, Weronika Dymara-Konopka, Sławomir Woźniak, Hanna Szmygin, Łukasz Światłowski, Bartosz Kłobuszewski, Karolina Nieoczym
article en
3 citations

Abstract

<b>Objective</b>: Cervical pregnancy (CP) accounts for less than 1% of all ectopic pregnancies. The standard of management for CP is still under detailed investigation; however, among the known treatment methods, super-selective uterine artery embolization (UAE) and the use of methotrexate (MTX) have emerged as effective and minimally invasive options in recent years. Our aim is to present our center's experience and provide available evidence evaluating the efficacy of UAE in the treatment of CP. <b>Materials and Methods:</b> This single-center and retrospective study evaluated the procedural and clinical outcomes of patients with CP who underwent endovascular uterine embolization with MTX between 2017 and 2024. Both procedural and clinical efficacy and safety, as well as the rate of complications and long-term outcomes, were noted. <b>Results:</b> A total of nine patients were diagnosed with CP (imaging examination included transvaginal ultrasound and/or magnetic resonance imaging) and referred for endovascular treatment. The mean age of the patients was 36.7 years, and the mean gestational age on admission was 9 weeks. In all cases, selective catheterization of supplying vessels and subsequent embolization with a mixture of methotrexate and gel sponge was carried out. The technical success rate was 100% with no complications. Follow-up ultrasound confirmed the disappearance of the flow signal around the intracervical gestational sac in all cases. <b>Conclusions:</b> In conclusion, this retrospective study demonstrated the procedural and clinical safety and efficacy of uterine artery embolization in patients with cervical pregnancy. This is why endovascular therapy should be proposed to these individuals and be included in treatment options discussed during multidisciplinary boards.

DiagnosticsVol. 15(15)
Medical University of Lublin (PL), Lublin Oncology Center (PL)
Good health and well-being
Openalex Percentile: Top 4%
Ectopic Pregnancy Diagnosis and Management
5.64
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