Impact of miR-181a on SIRT1 Expression and Senescence in Hutchinson–Gilford Progeria Syndrome
These findings highlight the important role of miR-181a-5p in premature aging and suggest its potential as a therapeutic target for modulating senescence in progeroid syndromes.
Authors
- Eva-Maria Lederer (ORCID: https://orcid.org/0000-0002-1220-1040)
- Felix Quirin Fenzl (ORCID: https://orcid.org/0009-0007-7762-5243)
- Karima Djabali (ORCID: https://orcid.org/0000-0003-4067-4977)
- Ramona Hartinger
- Moritz Schroll
- Peter Krüger
Institutions
- Technical University of Munich (DE)
Publication Details
- Journal
- Diseases
- Published
- 2025-08-04
- DOI
- https://doi.org/10.3390/diseases13080245
- Primary Topic
- Nuclear Structure and Function
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft