Ground Reaction Forces and Impact Loading Among Runners with Different Acuity of Tibial Stress Injuries: Advanced Waveform Analysis for Running Mechanics

Conventional ground reaction force (GRF) and load rate (LR) analyses may overlook temporal and waveform characteristics that reflect injury status and acuity. This study used an alternative GRF processing methodology to characterize GRF waveforms among runners with symptomatic medial tibial stress fractures (MTSS) and those recovering from tibial stress fractures (TSF; both unilateral [UL] and bilateral [BL]). This cross-sectional analysis of runners (<i>n</i> = 66) included four groups: symptomatic MTSS, recovering from UL or BL TSF, or uninjured case-matched controls. Participants ran at self-selected speed on an instrumented treadmill. Kinematics were collected with a 3D optical motion analysis system. Double-Gaussian models described the biphasic loading pattern of running gait (initial impact, active phases). Gaussian parameters described relative differences in the GRF waveform by injury condition. LR was calculated using the central difference numerical derivative of the raw normalized net force data. During the impact phase (0-20% of stance), controls and BL TSF produced higher GRF amplitudes than UL TSF and MTSS (<i>p</i> < 0.05). BL TSF and controls had greater maximal positive LR and minimum LR than UL TSF and MTSS. Peak medial GRF was 18-43% higher in the BL TSF group than in MTSS and UL TSF (<i>p</i> < 0.05). Correlations existed between tibial pain severity and early stance net GRF (r = 0.512; <i>p</i> = 0.016) and between pain severity and the duration since diagnosis for LR values during the impact phase (r values = 0.389-0.522; all <i>p</i> < 0.05). Collectively, these data suggest that this waveform modeling approach can differentiate injury status and pain acuity in runners. Early stance GRF and LR may offer novel insight into the management of running-related injuries.