Clove as a Versatile Resource: CuO Nanoparticles and Their Catalytic Role in Eugenol-Based Triazole Synthesis

As eco-friendly processes become central to modern organic synthesis, plant-based materials are emerging as attractive alternatives for both nanoparticle fabrication and catalysis. In this study, we explore the use of clove extract, a natural and renewable resource, for the green synthesis of copper oxide (CuO) nanoparticles and their subsequent application in organic transformations. Clove extract was employed to reduce copper chloride via a simple co-precipitation method under mild conditions, yielding CuO nanoparticles characterized by XRD, FTIR, and SEM-EDX techniques. These nanoparticles were then used as catalysts in the copper-catalyzed azide–alkyne cycloaddition (CuAAC) to afford eugenol-based 1,2,3-triazoles in excellent yields. This dual use of clove extract exemplifies a sustainable approach that merges natural product valorization with efficient catalysis for triazole synthesis.

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Journal
Processes
Published
2025-07-26
DOI
https://doi.org/10.3390/pr13082378
Citations
1
Primary Topic
Click Chemistry and Applications
Type
article
Field-Weighted Citation Impact
0.94
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article

Clove as a Versatile Resource: CuO Nanoparticles and Their Catalytic Role in Eugenol-Based Triazole Synthesis

Vittorio Pace, Mehdi Adjdir, Choukry Kamel Bendeddouche, Margherita Miele et al.
1 citations
Processes
Click Chemistry and Applications
0.94
article

Clove as a Versatile Resource: CuO Nanoparticles and Their Catalytic Role in Eugenol-Based Triazole Synthesis

Vittorio Pace, Mehdi Adjdir, Choukry Kamel Bendeddouche, Margherita Miele, Seif El Islam Lebouachera, Sérine Madji, Brahim Djemoui, Miloud Mazari, Sarra Zouaoui, Haroun Houicha
article en
1 citations

Abstract

As eco-friendly processes become central to modern organic synthesis, plant-based materials are emerging as attractive alternatives for both nanoparticle fabrication and catalysis. In this study, we explore the use of clove extract, a natural and renewable resource, for the green synthesis of copper oxide (CuO) nanoparticles and their subsequent application in organic transformations. Clove extract was employed to reduce copper chloride via a simple co-precipitation method under mild conditions, yielding CuO nanoparticles characterized by XRD, FTIR, and SEM-EDX techniques. These nanoparticles were then used as catalysts in the copper-catalyzed azide–alkyne cycloaddition (CuAAC) to afford eugenol-based 1,2,3-triazoles in excellent yields. This dual use of clove extract exemplifies a sustainable approach that merges natural product valorization with efficient catalysis for triazole synthesis.

ProcessesVol. 13(8)
Centre National de la Recherche Scientifique (FR), Université Oran 1 Ahmed Ben Bella (DZ), University of Sciences and Technology Houari Boumediene (DZ), University of Algiers Benyoucef Benkhedda (DZ), University of Biskra (DZ), Institut des Sciences Analytiques et de Physico-Chimie pour l'Environnement et les Matériaux (FR), Université de Saida Dr.Moulay Tahar (DZ), University of Turin (IT)
Responsible consumption and production
Openalex Percentile: Top 23%
Click Chemistry and Applications
0.94
DOIOpen Access PDFOpenAlex
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