Bacterial alarmone (p)ppGpp mediates the pathogenicity of <i>Clavibacter michiganensis</i> via a dual mechanism that affects both enzyme production and the Tat secretion system

This study reveals the pivotal role of the bacterial alarmone guanosine tetraphosphate and guanosine pentaphosphate in the pathogenicity of <i>Clavibacter michiganensis</i>, a significant plant pathogen. Through the identification of its dual mechanisms in regulating enzyme production and the Tat secretion system, we uncover key insights into bacterial virulence strategies. Our findings not only advance the understanding of bacterial stress response systems but also offer new opportunities for developing targeted interventions to combat plant bacterial diseases, ultimately contributing to agricultural sustainability and food security.