Care and Precautions for Immunization with Bacillus Calmette-Guérin

Camille Gurin administered, for the first time in humans, a vaccine capable of preventing tuberculosis (TB), a highly transmissible infectious disease associated with high mortality rates, particularly in socially vulnerable populations.This vaccine, called Bacillus Calmette-Gurin (BCG), was developed from an attenuated strain of Mycobacterium bovis, a mycobacterial species known to cause bovine TB 1 .With over a century of use, the BCG vaccine remains widely utilized worldwide for the prevention of severe forms of TB.In Brazil, it is part of the National Immunization Program and is provided by the Unified Health System (Sistema nico de Sade [SUS]) in multidose vials in a lyophilized form for vaccination of all newborns.After reconstitution with 0.9% saline solution, the vials must be stored refrigerated (2C to 8C) and protected from light to maintain stability for up to six hours.The BCG vaccine is