Multi-scale simulation of red blood cell trauma in large-scale high-shear flows after Norwood operation

The central shunt is more hemolytic in comparison to the modified Blalock-Taussig shunt. Between the two mBTSs, the smaller diameter is slightly more prone to hemolysis. Spatial damage maps produced based on the studied metrics, highlighted hot zones that match the clinical images of shunt thrombosis, demonstrating their potential to enhance cardiac surgery outcomes.

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Publication Details

Journal
Computer Methods and Programs in Biomedicine
Published
2025-07-19
DOI
https://doi.org/10.1016/j.cmpb.2025.108947
Primary Topic
Hydrology and Sediment Transport Processes
Type
article
Field-Weighted Citation Impact
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article

Multi-scale simulation of red blood cell trauma in large-scale high-shear flows after Norwood operation

Mahdi Esmaily, Shehab A. Mansour, James F. Antaki, E. Logan
Computer Methods and Programs in Biomedicine
Hydrology and Sediment Transport Processes
article

Multi-scale simulation of red blood cell trauma in large-scale high-shear flows after Norwood operation

Mahdi Esmaily, Shehab A. Mansour, James F. Antaki, E. Logan
article en

Abstract

The central shunt is more hemolytic in comparison to the modified Blalock-Taussig shunt. Between the two mBTSs, the smaller diameter is slightly more prone to hemolysis. Spatial damage maps produced based on the studied metrics, highlighted hot zones that match the clinical images of shunt thrombosis, demonstrating their potential to enhance cardiac surgery outcomes.

Computer Methods and Programs in BiomedicineVol. 271
Cornell University (US)
Openalex Percentile: Top 81%
Hydrology and Sediment Transport Processes
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