To elucidate the effect of Ruanjian Qingmai granules on arteriosclerosis obliterans from the perspective of cholesterol efflux
Ruanjian Qingmai granules exerts a therapeutic effect on ASO by up-regulating the expression level of <i>CYP7A1</i> mRNA, thereby reprogramming lipid metabolism. Kaempferol and isorhamnetin are likely the main active components of RJQM in lipid metabolic reprogramming.
Authors
- Tianhua Yan (ORCID: https://orcid.org/0000-0001-6124-8630)
- Chenglin Jia (ORCID: https://orcid.org/0000-0001-7108-5505)
- Guang‐Bo Ge (ORCID: https://orcid.org/0000-0002-9670-4349)
- Yemin Cao (ORCID: https://orcid.org/0000-0002-6617-8501)
- Yongbing Cao (ORCID: https://orcid.org/0000-0002-2344-1832)
- Biying Hong
- Yan Xie (ORCID: https://orcid.org/0000-0002-8428-1406)
- Yujie Jiang
- Chao Ma (ORCID: https://orcid.org/0000-0003-3665-9133)
- Wei Liu (ORCID: https://orcid.org/0000-0002-9302-8170)
- Yicheng Xu (ORCID: https://orcid.org/0000-0002-7751-622X)
- Jian Chen (ORCID: https://orcid.org/0000-0003-4756-7154)
Institutions
- China Pharmaceutical University (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai Traditional Chinese Medicine Hospital (CN)
- Shuguang Hospital (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-08-04
- DOI
- https://doi.org/10.3389/fmed.2025.1510927
- Citations
- 1
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 2.01