Can Large Language Models Accurately Generate Answer Keys for Health-related Questions?

The evaluation of text generated by large language models (LLMs) remains a challenge for question answering, retrieval augmented generation (RAG), summarization, and many other natural language processing tasks.Evaluating the factuality of LLM-generated responses is particularly important in medical question answering, where the stakes are high.One method of evaluating the factuality of text is through the use of information nuggets (answer keys).Nuggets are text representing atomic facts that may be used by an assessor to make a binary decision as to whether the fact represented by said nugget is contained in an answer.Given that manual nugget extraction is expensive and time-consuming, recent RAG shared task evaluations have explored automating the nuggetization of text with LLMs.In this work, we explore several approaches to nugget generation for medical question answering and evaluate their alignment with expert human nugget generation.We find providing an example and extracting nuggets from an answer to be the best approach to nuggetization.While, overall, we found the capabilities of LLMs to distill atomic facts limited, Llama 3.3 performed the best out of the models we tested.

Authors

Institutions

Publication Details

Published
2025-01-01
DOI
https://doi.org/10.18653/v1/2025.acl-short.28
Primary Topic
Topic Modeling
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Can Large Language Models Accurately Generate Answer Keys for Health-related Questions?

Dina Demner‐Fushman, Deepak Gupta, Dorothee B. Bartels
Topic Modeling
article

Can Large Language Models Accurately Generate Answer Keys for Health-related Questions?

Dina Demner‐Fushman, Deepak Gupta, Dorothee B. Bartels
article en

Abstract

The evaluation of text generated by large language models (LLMs) remains a challenge for question answering, retrieval augmented generation (RAG), summarization, and many other natural language processing tasks.Evaluating the factuality of LLM-generated responses is particularly important in medical question answering, where the stakes are high.One method of evaluating the factuality of text is through the use of information nuggets (answer keys).Nuggets are text representing atomic facts that may be used by an assessor to make a binary decision as to whether the fact represented by said nugget is contained in an answer.Given that manual nugget extraction is expensive and time-consuming, recent RAG shared task evaluations have explored automating the nuggetization of text with LLMs.In this work, we explore several approaches to nugget generation for medical question answering and evaluate their alignment with expert human nugget generation.We find providing an example and extracting nuggets from an answer to be the best approach to nuggetization.While, overall, we found the capabilities of LLMs to distill atomic facts limited, Llama 3.3 performed the best out of the models we tested.

United States National Library of Medicine (US)
National Institutes of Health, U.S. National Library of Medicine, NHLBI Division of Intramural Research
Quality Education
Openalex Percentile: Top 90%
Topic Modeling
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.