Impact of Carrying <i>DNMT3A</i> or <i>TET2</i> Mutations on Plaque Characteristics and Prognosis in Patients With STEMI Based on OCT
Patients with ST-segment-elevation myocardial infarction and <i>DNMT3A/TET2</i> mutations exhibit vulnerable characteristics in their coronary plaques, along with an increased risk of experiencing major adverse cardiovascular events. Moreover, carrying <i>TET2</i> mutations confers a worse prognosis compared with solely having <i>DNMT3A</i> mutations.
Authors
- Haibo Jia (ORCID: https://orcid.org/0000-0001-9968-4024)
- Shengfang Wang
- Boling Yi
- Bo Yu (ORCID: https://orcid.org/0000-0002-5955-6332)
- Minghao Liu (ORCID: https://orcid.org/0000-0002-8419-5233)
- Sining Hu (ORCID: https://orcid.org/0000-0002-8680-7045)
- Qianhui Sun
- Chen Zhao (ORCID: https://orcid.org/0000-0002-6753-7000)
- Ming Zeng (ORCID: https://orcid.org/0000-0003-2417-5561)
Institutions
- Harbin Medical University (CN)
- Second Affiliated Hospital of Harbin Medical University (CN)
- Heilongjiang University (CN)
Publication Details
- Journal
- Circulation Cardiovascular Imaging
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1161/circimaging.124.017915
- Citations
- 2
- Primary Topic
- Coronary Interventions and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 4.01