Oxygen Extraction Fraction on Baseline MRI Predicts Infarction Growth in Successfully Reperfused Patients
Our results showed penumbra-OEF<sub>r</sub> is a promising imaging biomarker for predicting infarct growth in acute ischemic stroke following successful reperfusion. Although elevation of penumbra-OEF<sub>r</sub> is protective, patients with lower penumbra-OEF<sub>r</sub> values sustained further ischemic injury and infarct growth.
Authors
- Luis Emilio Savastano (ORCID: https://orcid.org/0000-0002-9881-1594)
- David S. Liebeskind (ORCID: https://orcid.org/0000-0002-5109-8736)
- S. Andrew Josephson (ORCID: https://orcid.org/0000-0001-7502-550X)
- Kazim Narsinh (ORCID: https://orcid.org/0000-0002-2019-5461)
- David Saloner (ORCID: https://orcid.org/0000-0002-6989-8547)
- Matthew R. Amans (ORCID: https://orcid.org/0000-0002-8209-0534)
- Cathra Halabi (ORCID: https://orcid.org/0000-0002-0331-8183)
- Kambiz Nael (ORCID: https://orcid.org/0000-0002-4194-9488)
- Ahmad Fadzil Ismail (ORCID: https://orcid.org/0000-0002-3321-8546)
- Steven W. Hetts (ORCID: https://orcid.org/0000-0001-5885-7259)
- Nerissa Ko (ORCID: https://orcid.org/0000-0002-3439-0559)
- Mersedeh Bahr Hosseini (ORCID: https://orcid.org/0000-0003-3049-4542)
- Geoffrey P. Colby (ORCID: https://orcid.org/0000-0002-3376-0933)
- Jeffrey L. Saver (ORCID: https://orcid.org/0000-0001-9141-2251)
- Christopher Paul Hess (ORCID: https://orcid.org/0000-0002-5132-5302)
- Wade S. Smith (ORCID: https://orcid.org/0000-0003-4174-8333)
- Viktor Szeder (ORCID: https://orcid.org/0000-0003-0703-8258)
- Daniel L. Cooke (ORCID: https://orcid.org/0000-0002-3694-413X)
- Vivek Srikar Yedavalli (ORCID: https://orcid.org/0000-0002-2450-4014)
- Pouya Metanat (ORCID: https://orcid.org/0000-0003-2905-4080)
- Mona Asghariahmadabad
- Anthony Kim (ORCID: https://orcid.org/0000-0002-8095-6517)
Institutions
- Johns Hopkins University (US)
- University of California, Los Angeles (US)
- Johns Hopkins Medicine (US)
- Norwegian Womens Public Health Association (NO)
- Neurological Surgery (US)
Publication Details
- Journal
- Stroke
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1161/strokeaha.125.051270
- Citations
- 1
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 1.35