A case of ICIs-associated arthritis caused by Toripalimab initially presenting as oedema in both lower limbs
The use of immune checkpoint inhibitors (ICIs) has offered new hope for patients with malignant tumours; however, it is essential to acknowledge their potential toxic side effects. Among these, ICIs-associated arthritis (IA) is not uncommon but non-specific and lacks diagnostic criteria. In this case, a patient with advanced colon cancer developed IA following treatment with Toripalimab. Notably, the condition improved after the administration of steroids, and the tumour remains well-controlled. This case report significantly contributes to enhancing clinicians' understanding of IA.
Authors
- Hao Yang (ORCID: https://orcid.org/0000-0003-0814-6058)
- Junjun Shen (ORCID: https://orcid.org/0000-0001-8321-1521)
- J. Zhang
- Zhili Zhou (ORCID: https://orcid.org/0000-0002-5641-7169)
Institutions
- Huzhou Central Hospital (CN)
- Gaochun People's Hospital (CN)
Publication Details
- Journal
- Journal of Chemotherapy
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1080/1120009x.2025.2540173
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00