A case of ICIs-associated arthritis caused by Toripalimab initially presenting as oedema in both lower limbs

The use of immune checkpoint inhibitors (ICIs) has offered new hope for patients with malignant tumours; however, it is essential to acknowledge their potential toxic side effects. Among these, ICIs-associated arthritis (IA) is not uncommon but non-specific and lacks diagnostic criteria. In this case, a patient with advanced colon cancer developed IA following treatment with Toripalimab. Notably, the condition improved after the administration of steroids, and the tumour remains well-controlled. This case report significantly contributes to enhancing clinicians' understanding of IA.

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Publication Details

Journal
Journal of Chemotherapy
Published
2025-08-04
DOI
https://doi.org/10.1080/1120009x.2025.2540173
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
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article

A case of ICIs-associated arthritis caused by Toripalimab initially presenting as oedema in both lower limbs

Hao Yang, Junjun Shen, J. Zhang, Zhili Zhou
Journal of Chemotherapy
Cancer Immunotherapy and Biomarkers
article

A case of ICIs-associated arthritis caused by Toripalimab initially presenting as oedema in both lower limbs

Hao Yang, Junjun Shen, J. Zhang, Zhili Zhou
article en

Abstract

The use of immune checkpoint inhibitors (ICIs) has offered new hope for patients with malignant tumours; however, it is essential to acknowledge their potential toxic side effects. Among these, ICIs-associated arthritis (IA) is not uncommon but non-specific and lacks diagnostic criteria. In this case, a patient with advanced colon cancer developed IA following treatment with Toripalimab. Notably, the condition improved after the administration of steroids, and the tumour remains well-controlled. This case report significantly contributes to enhancing clinicians' understanding of IA.

Journal of Chemotherapy
Huzhou Central Hospital (CN), Gaochun People's Hospital (CN)
Openalex Percentile: Top 72%
Cancer Immunotherapy and Biomarkers
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A case of ICIs-associated arthritis caused by Toripalimab initially presenting as oedema in both lower limbs — Hao Yang, Junjun Shen, et al. · Journal of Chemotherapy (2025) | TGRS Research Map | TGRS