The Effect of Hyperoxia on Nitric Oxide Metabolism in the Skeletal Muscle of Male Type 2 Diabetic Rats
Hyperoxia decreased NO bioavailability in SM of rats with T2D; this effect was associated with decreased eNOS and increased arginase protein levels. These findings suggest that oxygen therapy in diabetic rats may decrease NO bioavailability as a potential side effect.
Authors
- Sajad Jeddi (ORCID: https://orcid.org/0000-0002-3911-6620)
- Asghar Ghasemi (ORCID: https://orcid.org/0000-0001-6867-2151)
- Reza Norouzirad (ORCID: https://orcid.org/0000-0002-5046-057X)
- Mohammad Vaez Mousavi
Institutions
- Research Institute for Endocrine Sciences (IR)
- Dezful University of Medical Sciences (IR)
- Shahid Beheshti University of Medical Sciences (IR)
Publication Details
- Journal
- Endocrinology Diabetes & Metabolism
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1002/edm2.70090
- Citations
- 1
- Primary Topic
- Nitric Oxide and Endothelin Effects
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Shahid Beheshti University of Medical Sciences