Aberrant Splicing Burden Predicts Immune Infiltration and Prognosis in Head and Neck Squamous Cell Carcinomas
High splicing burden, as defined by OutSplice, is a novel biomarker to predict poor both immune infiltration and prognosis in HNSC.
Authors
- Sandhya Kalavacherla (ORCID: https://orcid.org/0000-0003-0485-9042)
- Joseph A. Califano (ORCID: https://orcid.org/0000-0002-4715-6761)
- Theresa W. Guo (ORCID: https://orcid.org/0000-0002-1689-3275)
- Mitchell T. Victor (ORCID: https://orcid.org/0000-0002-5733-7048)
- Joseph Bendik (ORCID: https://orcid.org/0000-0003-0877-5639)
- Hannah Carter (ORCID: https://orcid.org/0000-0002-1729-2463)
Institutions
- Indiana University Health (US)
- UC San Diego Health System (US)
- University of California San Diego (US)
- University of California San Diego Medical Center (US)
- Urology of Indiana (US)
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- Head & Neck
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1002/hed.70007
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health