Cytomorphological Features of Fine Needle Aspiration in 11 Conventional and 2 Dedifferentiated Chordomas: Correlation With Histopathology

Chordoma shows distinctive yet variable cytomorphological features that can allow for a reliable diagnosis in FNA samples. Clinical and radiological correlation is essential to guide sampling, especially in the dedifferentiated cases, and avoid misinterpretation. Some cytological features typically associated with dedifferentiation may be present in conventional chordomas, underscoring the importance of cautious interpretation and histological confirmation.