Comparison of survival in patients with low <i>vs</i>. intermediate prostate-specific antigen concentrations and development of a nomogram: a surveillance, epidemiology and end results program database study with external validation on a Chinese coho
Our findings indicate that low PSA concentrations exert divergent impacts on prostate cancer patients stratified by T stage and GS. Specifically, in patients with high GS (8-10), low PSA concentrations represent a risk factor for disease progression to advanced stages and poor prognosis. Additionally, we developed a novel nomogram that effectively predicts survival outcomes in these patients.
Authors
- Guanqun Zhu (ORCID: https://orcid.org/0000-0001-7841-8026)
- Fengju Guan (ORCID: https://orcid.org/0000-0002-8560-9733)
- Jingchang Mei
- Lijiang Sun (ORCID: https://orcid.org/0000-0001-5856-8270)
- Guiming Zhang (ORCID: https://orcid.org/0000-0002-5856-5325)
- Yu Yao
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2025-08-04
- DOI
- https://doi.org/10.7717/peerj.19823
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Shandong Province