Pharmacokinetics of subcutaneous and intravenous bolus doses of morphine in palliative care cancer patients receiving infusion of morphine: A pharmacokinetic substudy of a randomized controlled trial
IV morphine showed faster absorption with substantially higher peak concentrations compared to SC. Further research is needed to assess the clinical relevance of these differences.
Authors
- Siri Steine
- Olav Magnus S. Fredheim (ORCID: https://orcid.org/0000-0002-0931-0027)
- Jūratė Šaltytė Benth (ORCID: https://orcid.org/0000-0003-4199-2272)
- Ola Dale (ORCID: https://orcid.org/0000-0001-9493-2658)
- Knut Magne Augestad (ORCID: https://orcid.org/0000-0002-4093-652X)
- Eva Gravdahl (ORCID: https://orcid.org/0009-0008-5264-0540)
Institutions
- University of Oslo (NO)
- Norwegian University of Science and Technology (NO)
- Akershus University Hospital (NO)
Publication Details
- Journal
- British Journal of Clinical Pharmacology
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1002/bcp.70191
- Primary Topic
- Pain Management and Opioid Use
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Helse Sør-Øst RHF