Optimal Tranexamic Acid Dosing for Adolescent Idiopathic Scoliosis Surgery

The tranexamic acid dose of 100 mg/kg bolus + 10 mg/kg/hr infusion (TXA 4) was the most effective in bleeding control during AIS instrumentation in teenagers. While these results are promising, more randomized trials are needed to directly compare various TXA doses.

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Publication Details

Journal
Spine
Published
2025-08-04
DOI
https://doi.org/10.1097/brs.0000000000005465
Primary Topic
Obstructive Sleep Apnea Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Optimal Tranexamic Acid Dosing for Adolescent Idiopathic Scoliosis Surgery

Ayesha Ayesha, Enzo von Quednow, Walter Fagundes, Nawal A. Rajab et al.
Spine
Obstructive Sleep Apnea Research
article

Optimal Tranexamic Acid Dosing for Adolescent Idiopathic Scoliosis Surgery

Ayesha Ayesha, Enzo von Quednow, Walter Fagundes, Nawal A. Rajab, Fabio Victor Vieira Rocha, Paweł Łajczak, Oguz Kagan Sahin, Yan Gabriel Morais David Silva, Yasmin Picanço Silva, Aisha Rizwan Ahmed, Paweł Chochoł, Martin Kotochinksy
article en

Abstract

The tranexamic acid dose of 100 mg/kg bolus + 10 mg/kg/hr infusion (TXA 4) was the most effective in bleeding control during AIS instrumentation in teenagers. While these results are promising, more randomized trials are needed to directly compare various TXA doses.

Spine
Balıkesir University (TR), University of Debrecen (HU), Universidad Nacional de Cuyo (AR), University of Iceland (IS), Medical University of Silesia (PL), Hospital Israelita Albert Einstein (BR), Sulaiman Al Rajhi Colleges (SA), State Hospital (GB), Jinnah Medical & Dental College (PK), Sivas State Hospital (TR), Hospital General Universitario de Albacete (ES), Hospital Universitari Sant Joan de Reus (ES), Complejo Hospitalario Universitario de Albacete (ES), University of Warmia and Mazury in Olsztyn (PL), Universidade Federal do Espírito Santo (BR)
Good health and well-being
Openalex Percentile: Top 75%
Obstructive Sleep Apnea Research
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Optimal Tranexamic Acid Dosing for Adolescent Idiopathic Scoliosis Surgery — Ayesha Ayesha, Enzo von Quednow, et al. · Spine (2025) | TGRS Research Map | TGRS