Label-free fluorescence lifetime imaging for real-time guidance of stereotactic biopsy: A feasibility study in brain cancer patients
Incorporating FLIm with standard stereotactic biopsy needle and workflow could provide real-time guidance in selecting biopsy targets along the needle's trajectory, potentially improving diagnostic yield and safety. This approach may also aid biopsy of other body tissues and the placement of brain probes treating functional disorders.
Authors
- Lisanne Kraft
- Han Sung Lee
- Alba Alfonso‐García (ORCID: https://orcid.org/0000-0002-6748-3751)
- Lee‐Way Jin (ORCID: https://orcid.org/0000-0001-9729-1032)
- Orin Bloch (ORCID: https://orcid.org/0000-0001-9810-6011)
- Julien Bec (ORCID: https://orcid.org/0000-0003-1222-4071)
- Laura Marcu (ORCID: https://orcid.org/0000-0003-2369-0748)
- Mohamed Abul Hassan
- Silvia Noble Anbunesan (ORCID: https://orcid.org/0000-0002-5003-6322)
- Matthew Bobinski (ORCID: https://orcid.org/0000-0002-8349-2084)
- Griffith R. Harsh
Institutions
- Neurological Surgery (US)
- University of California, Davis (US)
Publication Details
- Journal
- Neuro-Oncology Advances
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/noajnl/vdaf172
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- University of California, Davis
- Comprehensive Cancer Center, University of California, Davis