Identification of rs2036527 as a <i>cis</i>‐regulatory variant for <i>CHRNA3</i> and <i>CHRNA5</i> by allele‐specific expression and implications for nicotine dependence and lung cancer
This is the first report to indicate that rs2036527 genotype might be a better marker to predict the probability of developing nicotine dependence and that FOXA2, CHRNA5, and CHRNA3 might be treatment targets for nicotine dependence.
Authors
- Tao Peng (ORCID: https://orcid.org/0000-0002-4300-7806)
- Chang Sun (ORCID: https://orcid.org/0000-0002-2425-9485)
- Hao Guo (ORCID: https://orcid.org/0000-0001-6734-4164)
- Haiyan Li (ORCID: https://orcid.org/0000-0002-7423-2715)
- Xinxin Zhang (ORCID: https://orcid.org/0000-0002-0598-6425)
- Xiaoya Zhou (ORCID: https://orcid.org/0000-0002-6946-7122)
- Hongli Song (ORCID: https://orcid.org/0000-0003-1171-6074)
- Xiaoqian Shi
- Wei‐Ping Fu (ORCID: https://orcid.org/0009-0008-3705-6012)
Institutions
- Kunming Medical University (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
- Shaanxi Normal University (CN)
Publication Details
- Journal
- American Journal on Addictions
- Published
- 2025-08-03
- DOI
- https://doi.org/10.1111/ajad.70074
- Citations
- 1
- Primary Topic
- Nicotinic Acetylcholine Receptors Study
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China
- Fundamental Research Funds for the Central Universities