An anaplastic ependymoma with chondroid metaplasia after stereotactic radiosurgery: illustrative case
This is the fifth reported case of chondroid metaplasia in an ependymoma following radiotherapy. Once metaplasia occurs, the prognosis is highly unfavorable, particularly in anaplastic cases. Although proton therapy was administered under suboptimal conditions, the initial tumor control suggests it may be more effective if applied earlier. In the absence of effective chemotherapy, repeated minimally invasive surgeries and radiosurgeries may help preserve cognitive function and control disease progression. https://thejns.org/doi/10.3171/CASE25308.
Authors
- Hiromitsu Iwata
- Toshinori Hasegawa (ORCID: https://orcid.org/0000-0001-6535-0229)
- Yukio Seki (ORCID: https://orcid.org/0000-0001-9514-483X)
- Takenori Kato (ORCID: https://orcid.org/0000-0002-9270-2688)
- Takayuki Ishikawa (ORCID: https://orcid.org/0000-0002-4356-4039)
- Yugo Kishida
- Tetsuya Nagatani (ORCID: https://orcid.org/0000-0001-7705-5438)
Institutions
- University of Tokyo Hospital (JP)
- Komaki City Hospital (JP)
- Nagoya Medical Center (JP)
- Japanese Red Cross Nagoya Daini Hospital (JP)
- Daido University (JP)
Publication Details
- Journal
- Journal of Neurosurgery Case Lessons
- Published
- 2025-08-04
- DOI
- https://doi.org/10.3171/case25308
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00