The platelet concentrate storage environment may enhance the ability of <i>Cutibacterium acnes</i> to establish chronic infections
Our data demonstrated that the PC milieu enhances the ability of C. acnes to adhere to mammalian epithelia and promotes the expression of genes involved in invasion and persistence in host tissue, potentially priming this bacterium to cause chronic infections in transfusion patients, which warrants further investigation.
Authors
- Sandra Ramírez‐Arcos (ORCID: https://orcid.org/0000-0003-0705-4987)
- Dilini Kumaran
Institutions
- University of Ottawa (CA)
- Canadian Blood Services (CA)
Publication Details
- Journal
- Transfusion
- Published
- 2025-08-03
- DOI
- https://doi.org/10.1111/trf.18368
- Citations
- 2
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.54
Funders
- Canadian Blood Services
- Health Canada