Prevalence of liver disorders in children and adolescents with type 1 diabetes mellitus

Liver disorders in patients with T1DM are not as rare as previously thought, and glycogenic hepatopathy is the most common. A combination of liver enzymes and a liver ultrasound exam is a good initial screening and follow-up method for the evaluation of liver disorders. MRI represents a good non-invasive tool for the distinction between glycogen and fat accumulation, and might postpone liver biopsy beyond initial workup.

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Publication Details

Journal
BMC Pediatrics
Published
2025-08-04
DOI
https://doi.org/10.1186/s12887-025-05914-z
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Prevalence of liver disorders in children and adolescents with type 1 diabetes mellitus

Lucija Kolega Mrkic, Anita Špehar Uroić, Nevena Krnić, Mirna Aničić et al.
BMC Pediatrics
Liver Disease Diagnosis and Treatment
article

Prevalence of liver disorders in children and adolescents with type 1 diabetes mellitus

Lucija Kolega Mrkic, Anita Špehar Uroić, Nevena Krnić, Mirna Aničić, Marijana Ćorić, Jurica Vuković, Katja Dumić, Martina Zidanic
article en

Abstract

Liver disorders in patients with T1DM are not as rare as previously thought, and glycogenic hepatopathy is the most common. A combination of liver enzymes and a liver ultrasound exam is a good initial screening and follow-up method for the evaluation of liver disorders. MRI represents a good non-invasive tool for the distinction between glycogen and fat accumulation, and might postpone liver biopsy beyond initial workup.

BMC PediatricsVol. 25(1)
Holy Spirit Hospital (IN), University Hospital Centre Zagreb (HR), University of Zagreb (HR), Children's Hospital Zagreb (HR), University of Zadar (HR)
Good health and well-being
Openalex Percentile: Top 73%
Liver Disease Diagnosis and Treatment
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Prevalence of liver disorders in children and adolescents with type 1 diabetes mellitus — Lucija Kolega Mrkic, Anita Špehar Uroić, et al. · BMC Pediatrics (2025) | TGRS Research Map | TGRS