Metabolic engineering and adaptive laboratory evolution of Kluyveromyces Marxianus for lactic acid production
Our results highlight the potential of integrating state-of-the-art techniques with the genetic diversity of non-standard microbes to obtain superior microbial cell factories that can ferment xylose-containing media and can be harnessed for sustainable commercial production of fine chemicals through precision fermentation.
Authors
- Jeroen Bauwens (ORCID: https://orcid.org/0000-0003-0513-5900)
- Alexander DeLuna (ORCID: https://orcid.org/0000-0002-9236-2804)
- Eugenio Mancera (ORCID: https://orcid.org/0000-0003-0146-8732)
- Quinten Deparis (ORCID: https://orcid.org/0000-0003-4995-4369)
- H. T. Godoy
- J.B.M. Goossenaerts (ORCID: https://orcid.org/0000-0002-7359-5936)
- Raúl A. Ortiz‐Merino (ORCID: https://orcid.org/0000-0003-4186-8941)
- Kevin J. Verstrepen (ORCID: https://orcid.org/0000-0002-3077-6219)
- Jolien Smets (ORCID: https://orcid.org/0000-0002-2899-4639)
- Eva Van Bun
Institutions
- Instituto Tecnológico Superior de Irapuato (MX)
- Institute of Biochemistry and Biophysics, Polish Academy of Sciences (PL)
- Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (ES)
- Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (MX)
- KU Leuven (BE)
Publication Details
- Journal
- Microbial Cell Factories
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1186/s12934-025-02805-x
- Citations
- 3
- Primary Topic
- Microbial Metabolic Engineering and Bioproduction
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- Fonds Wetenschappelijk Onderzoek
- Consejo Nacional de Ciencia y Tecnología