Identification of IQGAP3 prognostic potential and involvement in immune cell infiltration in LUAD
Overexpression of IQGAP3 in LUAD is associated with poor clinical outcomes and promotes tumor progression by regulating cell cycle and inducing T cell exhaustion via RAS-ERK signaling pathway.
Authors
- Cheng‐xiong You
- Mingduan Chen
- Shuchen Chen (ORCID: https://orcid.org/0000-0002-3316-9908)
- Peipei Zhang (ORCID: https://orcid.org/0000-0003-4405-0432)
Institutions
- Fujian Medical University (CN)
- Union Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1186/s40001-025-02976-8
- Citations
- 1
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Natural Science Foundation of Fujian Province