Use of nomograms based on the one-compartment model in the estimation of area under the blood concentration–time curve of vancomycin: a retrospective cohort study
The estimation method utilising AUC nomograms and Vd<sub>,app</sub> represents a straightforward approach with accuracy comparable to that of the Bayesian method, suggesting its potential for clinical application. However, its implementation in cases of high clearance or in patients with severe infections warrants careful consideration.
Authors
- Aya Kawakami
- Go Okamoto (ORCID: https://orcid.org/0000-0001-7561-7791)
- Miki Sawai
- Daisuke Ito (ORCID: https://orcid.org/0000-0002-4740-1675)
- Emiko Kobayashi
- Kazuhiro Okano
Institutions
- Tokyo Women's Medical University (JP)
Publication Details
- Journal
- European Journal of Clinical Pharmacology
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1007/s00228-025-03885-9
- Citations
- 1
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 1.40