Gender differences in neurocognitive impairment among first-episode, drug-naïve schizophrenia patients: a cross-sectional study
FES manifests as sex-divergent cognitive profiles, with males showing executive/processing speed deficits tied to negative symptoms and females exhibiting memory impairments with broader symptom associations. These findings underscore the need for sex-sensitive approaches in characterizing cognitive dysfunction in early psychosis.
Authors
- HaiChun Liu
- MingLiang Ju
- Zhenghui Yi (ORCID: https://orcid.org/0000-0003-3546-3219)
- HuiRu Cui (ORCID: https://orcid.org/0000-0001-5171-1871)
- XiaoChen Tang (ORCID: https://orcid.org/0000-0003-3796-7111)
- Qing Zhang (ORCID: https://orcid.org/0000-0003-3522-1471)
- Lihua Xu (ORCID: https://orcid.org/0000-0002-2237-9336)
- Jin Gao
- Min Su (ORCID: https://orcid.org/0000-0001-8791-1648)
- Tianhong Zhang (ORCID: https://orcid.org/0000-0002-5379-7119)
- Yingying Tang
- Jijun Wang (ORCID: https://orcid.org/0000-0003-4536-9664)
- YanYan Wei (ORCID: https://orcid.org/0000-0002-8218-1954)
- AiMin Sui
Institutions
- Shanghai Jiao Tong University (CN)
- Nantong University (CN)
- Shanghai Mental Health Center (CN)
- Taizhou Second People's Hospital (CN)
- Second People's Hospital of NanTong (CN)
- Ningde Normal University (CN)
- Qilu Hospital of Shandong University (CN)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2025-08-04
- DOI
- https://doi.org/10.3389/fpsyt.2025.1642291
- Citations
- 1
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China