Case Report: Takotsubo cardiomyopathy caused by acute surgical pathology against the background of colorectal cancer

We present a case of Takotsubo cardiomyopathy (TCM) in a young woman who has developed necrosis and perforation of the sigmoid intestine with a spontaneous opening of the abscess in the abdominal cavity, which caused purulent peritonitis. The patient underwent emergency surgical intervention. The postoperative period was complicated by a clinic of acute respiratory failure and bilateral pneumonia. In five days after surgery, the patient developed laboratory and instrumental signs of acute myocardial infarction. Changes similar to myocardial infarction appeared on electrocardiogram (ECG). Echocardiography revealed akinesis of the apical segments of the left ventricle and the ejection fraction of the left ventricle was reduced (LVEF) from 63 to 31%-35%. The level of NT-proBNP has increased significantly, but the level of troponin I increased to a lesser extent. Coronary angiography demonstrated normal arteries without any obstruction. As a result, a diagnosis Takotsubo cardiomyopathy caused by acute surgical pathology was made. In the future, the patient was discharged in a stable state. Subsequent echocardiography showed normalization of the systolic function of the left ventricle, the disappearance of ECG changes, and a decrease in the level of specific cardiomarkers.

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Journal
Frontiers in Cardiovascular Medicine
Published
2025-08-04
DOI
https://doi.org/10.3389/fcvm.2025.1586353
Citations
1
Primary Topic
Takotsubo Cardiomyopathy and Associated Phenomena
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article
Field-Weighted Citation Impact
1.39
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article

Case Report: Takotsubo cardiomyopathy caused by acute surgical pathology against the background of colorectal cancer

Elena Kononova, Z. Z.A. Fashafsha, В. Э. Хороненко, V. I. Potievskaya et al.
1 citations
Frontiers in Cardiovascular Medicine
Takotsubo Cardiomyopathy and Associated Phenomena
1.39
article

Case Report: Takotsubo cardiomyopathy caused by acute surgical pathology against the background of colorectal cancer

Elena Kononova, Z. Z.A. Fashafsha, В. Э. Хороненко, V. I. Potievskaya, А. Д. Каприн, Elena Paderina
article en
1 citations

Abstract

We present a case of Takotsubo cardiomyopathy (TCM) in a young woman who has developed necrosis and perforation of the sigmoid intestine with a spontaneous opening of the abscess in the abdominal cavity, which caused purulent peritonitis. The patient underwent emergency surgical intervention. The postoperative period was complicated by a clinic of acute respiratory failure and bilateral pneumonia. In five days after surgery, the patient developed laboratory and instrumental signs of acute myocardial infarction. Changes similar to myocardial infarction appeared on electrocardiogram (ECG). Echocardiography revealed akinesis of the apical segments of the left ventricle and the ejection fraction of the left ventricle was reduced (LVEF) from 63 to 31%-35%. The level of NT-proBNP has increased significantly, but the level of troponin I increased to a lesser extent. Coronary angiography demonstrated normal arteries without any obstruction. As a result, a diagnosis Takotsubo cardiomyopathy caused by acute surgical pathology was made. In the future, the patient was discharged in a stable state. Subsequent echocardiography showed normalization of the systolic function of the left ventricle, the disappearance of ECG changes, and a decrease in the level of specific cardiomarkers.

Frontiers in Cardiovascular MedicineVol. 12
Peoples' Friendship University of Russia (RU), Sechenov University (RU), Federal Medical-Biological Agency (RU)
Good health and well-being
Openalex Percentile: Top 16%
Takotsubo Cardiomyopathy and Associated Phenomena
1.39
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Case Report: Takotsubo cardiomyopathy caused by acute surgical pathology against the background of colorectal cancer — Elena Kononova, Z. Z.A. Fashafsha, et al. · Frontiers in Cardiovascular Medicine (2025) | TGRS Research Map | TGRS