TLR3 rs3775291 C/T polymorphism is associated with elevated IFN-α level in asymptomatic HTLV-1 infection
Although polymorphisms in the TLR3 gene have not been associated with the presence of symptoms of HTLV-1-related inflammatory diseases, the <i>TLR3</i> rs3775291 C/T polymorphism appears to contribute to a better evolution of the HTLV-1 infection status and inflammatory process among asymptomatic individuals.
Authors
- Ricardo Ishak (ORCID: https://orcid.org/0000-0002-4741-6201)
- Sandra Souza Lima (ORCID: https://orcid.org/0000-0001-6800-7637)
- Antônio Carlos Rosário Vallinoto (ORCID: https://orcid.org/0000-0003-1135-6507)
- Izaura Maria Vieira Cayres Vallinoto (ORCID: https://orcid.org/0000-0003-1408-8384)
- Maria Alice Freitas Queiroz (ORCID: https://orcid.org/0000-0003-2014-2770)
- Wandrey Roberto dos Santos Brito
- F. Ferreira (ORCID: https://orcid.org/0000-0002-2225-1674)
- Aline Cecy Rocha de Lima (ORCID: https://orcid.org/0000-0001-5887-3689)
- António Oliveira (ORCID: https://orcid.org/0000-0001-6499-9552)
- Marco Túlio de Souza (ORCID: https://orcid.org/0000-0003-3133-4778)
- Carlos Araújo da Costa (ORCID: https://orcid.org/0000-0003-2662-3989)
- Emmanuelle Giuliana Mendes Santana
- Ednelza da Silva Graça Amoras
Institutions
- Instituto Federal de Educação, Ciência e Tecnologia do Pará (BR)
- Universidade Federal do Pará (BR)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-08-04
- DOI
- https://doi.org/10.3389/fcimb.2025.1604259
- Primary Topic
- T-cell and Retrovirus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico