GABA receptor antagonism elicits feeding in the septohypothalamic nucleus

Our findings suggest that GABA<sub>A</sub> or GABA<sub>B</sub> receptor deactivation by antagonists elicited eating with a delayed effect and increased general arousal in rats. These findings collectively suggest that SHy neurons expressing GABA<sub>A</sub> and/or GABA<sub>B</sub> receptors are elements of a neurocircuit that participates in the regulation of feeding.

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Publication Details

Journal
Frontiers in Behavioral Neuroscience
Published
2025-08-04
DOI
https://doi.org/10.3389/fnbeh.2025.1633659
Primary Topic
Neuroendocrine regulation and behavior
Type
article
Field-Weighted Citation Impact
0.00
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article

GABA receptor antagonism elicits feeding in the septohypothalamic nucleus

Ivett Gabriella, B. Glenn Stanley, Jonathan H. Dang, Chen Kuang et al.
Frontiers in Behavioral Neuroscience
Neuroendocrine regulation and behavior
article

GABA receptor antagonism elicits feeding in the septohypothalamic nucleus

Ivett Gabriella, B. Glenn Stanley, Jonathan H. Dang, Chen Kuang, Vandana Nambiar, Abinanda Mukundan, Aneerudh Venkatraghavan
article en

Abstract

Our findings suggest that GABA<sub>A</sub> or GABA<sub>B</sub> receptor deactivation by antagonists elicited eating with a delayed effect and increased general arousal in rats. These findings collectively suggest that SHy neurons expressing GABA<sub>A</sub> and/or GABA<sub>B</sub> receptors are elements of a neurocircuit that participates in the regulation of feeding.

Frontiers in Behavioral NeuroscienceVol. 19
University of California, Riverside (US)
Openalex Percentile: Top 78%
Neuroendocrine regulation and behavior
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