A study on the distribution of interleukin-10 gene polymorphisms and their association with febrile seizure susceptibility in children from the Wenzhou region, Zhejiang Province

Reduced IL-10 levels and specific IL-10 gene polymorphisms, particularly rs1800896 and rs1800872, were associated with increased susceptibility to febrile seizures in children from Wenzhou. These findings may inform early diagnostic markers, risk stratification tools, and potentially guide personalized treatment strategies for children at higher risk of FS.

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Publication Details

Journal
Frontiers in Public Health
Published
2025-08-04
DOI
https://doi.org/10.3389/fpubh.2025.1645018
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

A study on the distribution of interleukin-10 gene polymorphisms and their association with febrile seizure susceptibility in children from the Wenzhou region, Zhejiang Province

Ziliang Lin, Zhenyao Ding, Liqiang Lu, Heng Huang et al.
Frontiers in Public Health
Epilepsy research and treatment
article

A study on the distribution of interleukin-10 gene polymorphisms and their association with febrile seizure susceptibility in children from the Wenzhou region, Zhejiang Province

Ziliang Lin, Zhenyao Ding, Liqiang Lu, Heng Huang, Xiaojuan Lv, T. Eng Gan
article en

Abstract

Reduced IL-10 levels and specific IL-10 gene polymorphisms, particularly rs1800896 and rs1800872, were associated with increased susceptibility to febrile seizures in children from Wenzhou. These findings may inform early diagnostic markers, risk stratification tools, and potentially guide personalized treatment strategies for children at higher risk of FS.

Frontiers in Public HealthVol. 13
People's Hospital of Cangzhou (CN), Wenzhou City People's Hospital (CN)
Health Research
Openalex Percentile: Top 77%
Epilepsy research and treatment
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