Relationship between cerebrospinal fluid catecholamines levels and biomarkers of Alzheimer’s disease, inflammation and neuronal injury

Since neurofilaments are associated with neuronal damage, decreased L-DOPA levels in AD could be related to neuronal destruction. Catecholaminergic dysregulation seen in AD seems independent of β-amyloid and p-tau pathology.

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Publication Details

Journal
Neurological Research
Published
2025-08-03
DOI
https://doi.org/10.1080/01616412.2025.2542944
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Relationship between cerebrospinal fluid catecholamines levels and biomarkers of Alzheimer’s disease, inflammation and neuronal injury

Joana Guimarães, María José Sá, Paula Serrão, Lucinda Sequeira et al.
Neurological Research
Alzheimer's disease research and treatments
article

Relationship between cerebrospinal fluid catecholamines levels and biomarkers of Alzheimer’s disease, inflammation and neuronal injury

Joana Guimarães, María José Sá, Paula Serrão, Lucinda Sequeira, Maria Augusta Vieira‐Coelho, Isabel Moreira
article en

Abstract

Since neurofilaments are associated with neuronal damage, decreased L-DOPA levels in AD could be related to neuronal destruction. Catecholaminergic dysregulation seen in AD seems independent of β-amyloid and p-tau pathology.

Neurological Research
Fernando Pessoa University (PT), Hospital de São João (PT), Administração Regional de Saúde de Lisboa e Vale do Tejo (PT), Instituto de Saúde (BR), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
Good health and well-being
Openalex Percentile: Top 75%
Alzheimer's disease research and treatments
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