Analysis and validation of novel biomarkers related to palmitoylation in adenomyosis

In this study, we successfully identified diagnostic biomarkers for adenomyosis using comprehensive bioinformatics analysis and machine learning methods, and validated them with nomogram and ROC curves. Our findings provide new perspectives for understanding the pathogenesis of palmitoylation-related genes in adenomyosis and offer potential targets for the development of new therapeutic strategies.

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Publication Details

Journal
Frontiers in Genetics
Published
2025-08-04
DOI
https://doi.org/10.3389/fgene.2025.1614573
Primary Topic
Endometriosis Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Analysis and validation of novel biomarkers related to palmitoylation in adenomyosis

Hongwen Zhu, Huijuan Cao, Yue‐Chen Zhao, Yufeng Li et al.
Frontiers in Genetics
Endometriosis Research and Treatment
article

Analysis and validation of novel biomarkers related to palmitoylation in adenomyosis

Hongwen Zhu, Huijuan Cao, Yue‐Chen Zhao, Yufeng Li, Hongyu Zhang, Taotao Qin
article en

Abstract

In this study, we successfully identified diagnostic biomarkers for adenomyosis using comprehensive bioinformatics analysis and machine learning methods, and validated them with nomogram and ROC curves. Our findings provide new perspectives for understanding the pathogenesis of palmitoylation-related genes in adenomyosis and offer potential targets for the development of new therapeutic strategies.

Frontiers in GeneticsVol. 16
Lanzhou University Second Hospital (CN), Lanzhou University (CN)
Lanzhou University, National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 73%
Endometriosis Research and Treatment
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