From venoms to vanity: Exploring animal toxins as cosmeceuticals

The integration of biologically active compounds into cosmetics has led to the emergence of cosmeceuticals, bridging the gap between traditional skincare and pharmaceutical applications. While animal venoms have long been studied for their therapeutic potential, their role in cosmetic formulations remains underexplored. This mini-review examines the current scientific landscape regarding venom-derived bioactive compounds in cosmeceuticals, excluding botulinum toxin. Our analysis reveals a growing interest in bee venom and snake-derived peptides, with additional reports on spider and salamander toxins. These compounds exhibit promising properties, including anti-aging effects, skin healing, and facial muscle relaxation. However, regulatory challenges, ethical concerns, and gaps in scientific literature hinder their widespread adoption. This review highlights the need for further research to establish safety, efficacy, and sustainable sourcing practices, paving the way for venom-based innovations in modern skincare.