mRNA Expression to Assess Hypoxia and Angiogenesis in Decidual Tissue of Term Fetuses With a Congenital Heart Disease

Fetal hypoxia and altered angiogenesis on the level of mRNA expression in decidual tissue were not significantly different between CHD cases and controls and between cases with fetal simple TGA and cases with fetal left sided CHD. We hypothesize that other (angio) genetic and molecular pathways lead to morphological placental alterations in pregnancies with fetal CHD.

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Publication Details

Journal
Prenatal Diagnosis
Published
2025-08-03
DOI
https://doi.org/10.1002/pd.6870
Primary Topic
Congenital Heart Disease Studies
Type
article
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article

mRNA Expression to Assess Hypoxia and Angiogenesis in Decidual Tissue of Term Fetuses With a Congenital Heart Disease

Monique C. Haak, Maartje C. Snoep, Marie‐Louise van der Hoorn, Jacqueline D.H. Anholts et al.
Prenatal Diagnosis
Congenital Heart Disease Studies
article

mRNA Expression to Assess Hypoxia and Angiogenesis in Decidual Tissue of Term Fetuses With a Congenital Heart Disease

Monique C. Haak, Maartje C. Snoep, Marie‐Louise van der Hoorn, Jacqueline D.H. Anholts, Michael Eikmans, Moska Aliasi, Lotte E. van der Meeren, M. Ruiter
article en

Abstract

Fetal hypoxia and altered angiogenesis on the level of mRNA expression in decidual tissue were not significantly different between CHD cases and controls and between cases with fetal simple TGA and cases with fetal left sided CHD. We hypothesize that other (angio) genetic and molecular pathways lead to morphological placental alterations in pregnancies with fetal CHD.

Prenatal DiagnosisVol. 45(11)
Leiden University Medical Center (NL), Erasmus MC (NL)
Good health and well-being
Openalex Percentile: Top 73%
Congenital Heart Disease Studies
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