Research Progress of UHR and Coronary Heart Disease

冠状动脉粥样硬化性心脏病(Serum uric acid to high-density lipoprotein cholesterol ratio, UHR)是全球死亡的主要原因，随着饮食结构的改变，我国CHD的发病率呈逐年递增趋势。最近，血清尿酸与高密度脂蛋白胆固醇比值(Serum uric acid to High-density Lipoprotein cholesterol ratio, UHR)被报道为一种新的炎症和代谢标志物，它将CHD的致病因素与保护因素相结合。有研究表明，UHR是CHD的独立危险因素。本文将对UHR与CHD致病机制作一篇综述，旨在加强日常诊疗中对复合型指标的重视，使广大患者受益。Coronary Heart Disease (CHD) is a leading cause of death globally. With changes in dietary patterns, the incidence of CHD in China has shown a year-by-year increasing trend. Recently, the serum uric acid to high-density lipoprotein cholesterol ratio (UHR) has been reported as a novel inflammatory and metabolic biomarker that integrates both pathogenic and protective factors of CHD. Studies indicate that UHR is an independent risk factor for CHD. This review will explore the relationship between UHR and the pathogenic mechanisms of CHD, aiming to enhance the emphasis on composite indicators in routine clinical diagnosis and treatment, thereby benefiting a broad range of patients.