High seroprevalence of Rickettsia spp. and molecular detection of Rickettsia amblyommatis in human-biting ticks from the eastern Amazon, Brazil
This is the first study to detect anti-Rickettsia antibodies in humans and to identify R. amblyommatis in ticks parasitizing humans in the Amazon biome. The detection of R. amblyommatis in human-biting ticks, together with concurrent seropositivity in human sera from the same region, supports the hypothesis that this agent is actively circulating in the Amazon biome and may be responsible for undiagnosed cases of nonlethal spotted fever in the area.
Authors
- Felipe da Silva Krawczak (ORCID: https://orcid.org/0000-0002-3817-225X)
- Hermes Ribeiro Luz
- Leonardo Teixeira Dall’Agnol (ORCID: https://orcid.org/0000-0003-0837-8836)
- Raphaela Bueno Mendes Bittencourt (ORCID: https://orcid.org/0000-0001-7944-5122)
- Thiago Fernandes Martins (ORCID: https://orcid.org/0000-0002-7325-3362)
- M. Ferreira (ORCID: https://orcid.org/0000-0003-4833-351X)
- Marcelo B. Labruna (ORCID: https://orcid.org/0000-0002-9675-3132)
- R. M. Silva (ORCID: https://orcid.org/0009-0005-2430-6084)
- Rafael Michael Silva Nogueira
- Mayara Ingrid Sousa Lima (ORCID: https://orcid.org/0000-0002-1033-1984)
- Lívio Martins Costa (ORCID: https://orcid.org/0000-0002-1475-049X)
- Lina C. Binder (ORCID: https://orcid.org/0000-0002-2136-7149)
- Carlos Celso Mendonça Ramos
Institutions
- Universidade de São Paulo (BR)
- Universidade Ceuma (BR)
- Universidade Estadual do Maranhão (BR)
- Universidade Federal do Maranhão (BR)
- Universidade Federal de Goiás (BR)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1186/s13071-025-06944-3
- Citations
- 1
- Primary Topic
- Vector-borne infectious diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.05
Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Universidade Federal do Maranhão