Genetic Association and Causal Effects Between Obesity and Multiple Sclerosis: A Robust Two-Sample Mendelian Randomization Study

This study provides evidence that an increase in body size (BMI) can lead to MS. Therefore, maintaining a healthy weight during early life could be a potential strategy to reduce MS risk.

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Publication Details

Journal
Cureus
Published
2025-08-03
DOI
https://doi.org/10.7759/cureus.89287
Primary Topic
Genetic Associations and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Genetic Association and Causal Effects Between Obesity and Multiple Sclerosis: A Robust Two-Sample Mendelian Randomization Study

Abdulaziz Almosallam
Cureus
Genetic Associations and Epidemiology
article

Genetic Association and Causal Effects Between Obesity and Multiple Sclerosis: A Robust Two-Sample Mendelian Randomization Study

Abdulaziz Almosallam
article en

Abstract

This study provides evidence that an increase in body size (BMI) can lead to MS. Therefore, maintaining a healthy weight during early life could be a potential strategy to reduce MS risk.

CureusVol. 17(8)
Majmaah University (SA)
Zero hunger
Openalex Percentile: Top 78%
Genetic Associations and Epidemiology
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Genetic Association and Causal Effects Between Obesity and Multiple Sclerosis: A Robust Two-Sample Mendelian Randomization Study — Abdulaziz Almosallam · Cureus (2025) | TGRS Research Map | TGRS