Prediction of protein–protein interaction based on interaction-specific learning and hierarchical information
Overall, the proposed HI-PPI effectively addresses the limitations of existing PPI prediction methods. By leveraging the hierarchical structure of PPI network, HI-PPI significantly enhances the accuracy and robustness of PPI predictions.
Authors
- Weizhuo Li (ORCID: https://orcid.org/0000-0002-2298-2901)
- Jing Jiang (ORCID: https://orcid.org/0000-0002-5648-2323)
- Xiaofeng Cao (ORCID: https://orcid.org/0000-0002-7391-0334)
- Tao Tang (ORCID: https://orcid.org/0000-0002-1207-4192)
- Sisi Yuan
- Peng Wang (ORCID: https://orcid.org/0000-0001-9895-394X)
- Yuansheng Liu (ORCID: https://orcid.org/0000-0002-7680-3155)
- Taiguang Shen
Institutions
- Tongji University (CN)
- Hunan University (CN)
- Nanjing University of Posts and Telecommunications (CN)
Publication Details
- Journal
- BMC Biology
- Published
- 2025-08-03
- DOI
- https://doi.org/10.1186/s12915-025-02359-9
- Citations
- 2
- Primary Topic
- Protein Structure and Dynamics
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China