Plasma‐Driven Monocyte Dysfunction Drives Disease Progression in Alcohol‐Related Acute‐on‐Chronic Liver Failure

Our findings reveal monocyte dysfunction and plasma-induced immune alterations as key contributors to A-ACLF pathogenesis and prognosis. Targeting plasma-derived inflammatory mediators may offer novel therapeutic strategies.

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Publication Details

Journal
Journal of Gastroenterology and Hepatology
Published
2025-08-03
DOI
https://doi.org/10.1111/jgh.70053
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Plasma‐Driven Monocyte Dysfunction Drives Disease Progression in Alcohol‐Related Acute‐on‐Chronic Liver Failure

B. Vijayalekshmi, Uday Zachariah, Ashish Goel, C. E. Eapen et al.
Journal of Gastroenterology and Hepatology
Liver Disease Diagnosis and Treatment
article

Plasma‐Driven Monocyte Dysfunction Drives Disease Progression in Alcohol‐Related Acute‐on‐Chronic Liver Failure

B. Vijayalekshmi, Uday Zachariah, Ashish Goel, C. E. Eapen, Anand Sharma, Savit B. Prabhu, Anita Chaudhary, K.A. Balasubramanian
article en

Abstract

Our findings reveal monocyte dysfunction and plasma-induced immune alterations as key contributors to A-ACLF pathogenesis and prognosis. Targeting plasma-derived inflammatory mediators may offer novel therapeutic strategies.

Journal of Gastroenterology and HepatologyVol. 40(10)
Christian Medical College, Vellore (IN), Christian Medical College (IN)
Good health and well-being
Openalex Percentile: Top 73%
Liver Disease Diagnosis and Treatment
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