Bilateral acute iris transillumination following human immunodeficiency virus infection

Abstract Bilateral acute iris transillumination (BAIT) syndrome is an uncommon condition characterized by the abrupt dispersion of pigments into the anterior chamber, iris sphincter paralysis, and an increase in intraocular pressure. It is associated with viral infections and the administration of fluoroquinolone antibiotics, particularly moxifloxacin. This study presents a case of a 46-year-old woman who had human immunodeficiency virus infection and who developed BAIT syndrome 2 weeks after receiving systemic treatments, including bictegravir, emtricitabine, and sulfamethoxazole–trimethoprim. The patient was effectively treated with topical prednisolone acetate and antiglaucoma medications. Further studies are needed to investigate the relationship between human immunodeficiency virus infection and BAIT to improve the understanding of its pathophysiology.