Evaluation and Comparison of Ketoconazole and Alkaline Glutaraldehyde Effects on Candida albicans Adherence to Three Denture Base Materials: An In Vitro Study
Both ketoconazole and alkaline glutaraldehyde effectively reduced <i>C. albicans</i> adherence, but alkaline glutaraldehyde demonstrated a faster and more potent antimicrobial action, particularly on injectable denture materials, making it suitable for rapid disinfection. Ketoconazole showed gradual and sustained efficacy, which is ideal for long-term fungal control.
Authors
- Gudikandula Krishna
- Gottumukkala Vineela
- Palakayala Balaswamy
- Deepthi Batthula
- Rophica J Mitta
- Shyni R Gorremutchu
Institutions
- Kamineni Institute of Dental Sciences (IN)
Publication Details
- Journal
- Cureus
- Published
- 2025-08-03
- DOI
- https://doi.org/10.7759/cureus.89273
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00