Study on the Molecular Mechanism of Angiotensin Promoting the Process of Intrauterine Adhesions by Regulating the NLRP3 Inflammasome Pathway.
This study demonstrates that angiotensin II drives intrauterine adhesion progression through NLRP3 inflammasome-mediated inflammatory escalation and fibrotic remodeling. The identified Ang II-NLRP3 axis may offer a dual therapeutic target for mitigating both pathological inflammation and endometrial fibrosis in adhesion prevention.
Authors
- Song Lihua
- Tieying Shan
- Ansheng Cai
- Xiaonan Jia (ORCID: https://orcid.org/0000-0002-3725-6769)
- Zhiying Li (ORCID: https://orcid.org/0000-0003-3347-5486)
- Jinghong Ma (ORCID: https://orcid.org/0000-0002-3458-1363)
- Junjiao Li (ORCID: https://orcid.org/0000-0003-3355-5865)
- Junjun Fan
Institutions
- Hebei University of Engineering (CN)
- Handan College (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-05-01
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00