Recent Advances in Nanosponges as Drug Delivery System

The most recent developments in nanotechnology have led to the creation of a targeted medicine delivery system.A specialized medication delivery mechanism is necessary, nevertheless, in order to effectively target a molecule to a particular location.The development of nanosponge has been a significant stride in addressing issues like limited bioavailability and drug toxicity.Nanosponges, which are three-dimensional drug transporters at the nanoscale, are created by crosslinking polymers.The ability to hold a range of pharmaceuticals in various sizes is one advantage they provide.Because they may offer targeted drug delivery along with a regulated drug release pattern, nanosponges are better than alternative delivery methods.Nanosponges are microscopic sponges that are roughly the size of viruses (250 nm-1 m).They have chambers that can hold a wide range of medications.When it comes to regulated drug distribution, nanosponge is essential.Because it can load water and lipid-soluble drug molecules and lessen their side effects, it can increase the aqueous solubility and penurious bioavailability of medications in a variety of dosage forms for controlled drug administration, including oral, parenteral, topical, rectal, and inhalational dose forms.This review explores the advantages and disadvantages, methods of preparation, variables that affect their preparation, methods of characterization, uses, and the latest developments in nanosponges.The preparation process, characterization, and potential usage in drug delivery systems are the main topics of the current review.