A Comprehensive Review on The Aspect of Green Analytical Chemistry in Pharmaceutical Analysis

The aim of this review is to elaborate the concept of Green Analytical Chemistry and explore its utility in pharmaceutical analysis sector.Several article and literature reviews were studied to understand the concept of Green Analytical Chemistry and the impact it has in safeguarding the environment and ensuring sustainability of resources.The 12 principles of Green Analytical Chemistry have contributed significantly in implementing Green Analytical Chemistry in the agricultural, industrial as well as petrochemical sector.Metrices like Analytical Eco-Scale, Analytical Greenness, Atomic Efficiency Score and Green Analytical Procedure Index have proved to be a significant contributor in analysing the greenness of the analytical procedures and techniques.It is essential to understand the strategies that are required for implementing Green Analytical Chemistry in pharmaceutical analysis like miniaturization, green solvent usage, energy efficient technologies, automation & online analysis.The challenges & limitations of Green Analytical Chemistry like economic and logistical barriers to adopting green methods, balancing green practices with regulatory requirements and analytical performance, etc need to be overcome efficiently in order to ensure their optimum application and implementation in the coming future.The future perspectives of Green Analytical Chemistry including role of artificial intelligence and machine learning in optimizing green methods & potential for integrating Green Analytical Chemistry with other sustainable practices in the pharmaceutical industry need to be given special emphasis to maximise the benefits of Green Analytical Chemistry in the coming future.