Amblyostatin-1, the first salivary cystatin with host immunomodulatory and anti-inflammatory properties from the Neotropical tick <i>Amblyomma sculptum</i>, vector of Brazilian spotted fever.

These findings establish Amblyostatin-1 as a novel salivary cystatin with immunomodulatory and anti-inflammatory properties, highlighting its potential as an immunobiological agent.

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Publication Details

Journal
PubMed
Published
2025-01-01
DOI
https://doi.org/10.3389/fimmu.2025.1585703
Primary Topic
Vector-borne infectious diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Amblyostatin-1, the first salivary cystatin with host immunomodulatory and anti-inflammatory properties from the Neotropical tick Amblyomma sculptum, vector of Brazilian spotted fever.

Michail Kotsyfakis, Zdeněk Franta, Mohamed Amine Jmel, José M. Medina et al.
PubMed
Vector-borne infectious diseases
article

Amblyostatin-1, the first salivary cystatin with host immunomodulatory and anti-inflammatory properties from the Neotropical tick Amblyomma sculptum, vector of Brazilian spotted fever.

Michail Kotsyfakis, Zdeněk Franta, Mohamed Amine Jmel, José M. Medina, Josiane Betim de Assis, Aparecida S. Tanaka, Andréa Cristina Fogaça, Lucas Tirloni, Gabriel Cerqueira Alves Costa, Eliane Esteves, Anderson Sá‐Nunes, Wilson Santos Molari, Alan Frazão-Silva, Júlia Moura Bernardi, Gretta Huamanrayme, Solange Cristina Antão
article en

Abstract

These findings establish Amblyostatin-1 as a novel salivary cystatin with immunomodulatory and anti-inflammatory properties, highlighting its potential as an immunobiological agent.

PubMedVol. 16
Centre National de la Recherche Scientifique (FR), Sewanee: The University of the South (US), Universidad de Granada (ES), Universidade de São Paulo (BR), University of South Bohemia in České Budějovice (CZ), Institute of Parasitology of the Slovak Academy of Sciences (SK), National Institute of Allergy and Infectious Diseases (US), Ingénierie Moléculaire et Physiopathologie Articulaire (FR), Institute of Biomedical Science (GB), National Institute of Science and Technology (ID), University of South Alabama (US), Universidade Federal de São Paulo (BR), Foundation for Research and Technology Hellas (GR), Université de Lorraine (FR)
Fundação de Amparo à Pesquisa do Estado de São Paulo, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Conselho Nacional de Desenvolvimento Científico e Tecnológico, European Regional Development Fund, National Institute of Allergy and Infectious Diseases
Good health and well-being
Openalex Percentile: Top 80%
Vector-borne infectious diseases
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