Age-dependent impact of Zoledronic acid on periodontal structures under orthodontic loading
ZOL intake influenced the alveolar bone, periodontal ligament, cementum, blood vessel count, and tooth displacement under orthodontic force. The extent of these changes was age dependent, with distinct effects observed in juvenile and adult mice. Juvenile mice analyzed in the latency phase of medication exhibited behaviors resembling those of adult mice.
Authors
- Ana Zilda Nazar Bergamo (ORCID: https://orcid.org/0000-0002-3313-2152)
- Ariane Zamarioli (ORCID: https://orcid.org/0000-0002-7939-0528)
- Renato Côrrea Viana Casarin (ORCID: https://orcid.org/0000-0003-1743-5855)
- Francisco José Albuquerque de Paula (ORCID: https://orcid.org/0000-0003-1262-3486)
- Marília Pacífico Lucisano (ORCID: https://orcid.org/0000-0002-6866-0561)
- Paulo Nelson‐Filho (ORCID: https://orcid.org/0000-0001-8802-6480)
- Alberto Consolaro (ORCID: https://orcid.org/0000-0002-5902-5646)
- Letícia Fernanda Duffles
- Léa Assed Bezerra da Silva (ORCID: https://orcid.org/0000-0001-7118-6859)
- Murilo Fernando Neuppmann Feres
Institutions
- Universidade de Ribeirão Preto (BR)
- Universidade de São Paulo (BR)
- Methodist University of Piracicaba (BR)
- Clinics Hospital of Ribeirão Preto (BR)
- Hospital Bandeirantes (BR)
Publication Details
- Journal
- European Journal of Orthodontics
- Published
- 2025-06-12
- DOI
- https://doi.org/10.1093/ejo/cjaf032
- Citations
- 1
- Primary Topic
- Bone health and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico