Evaluation of the AIX1000 automated rapid plasma reagin test in a tertiary academic medical center

The AIX1000 showed good concordance with manual RPR, particularly at lower titers, with reliable analytical performance and operational advantages. However, systematic titer underestimation compared to manual RPR, particularly in high-titer samples, may affect clinical interpretation if tests are transitioned. Clinicians should be informed of this discrepancy when transitioning platforms.

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Publication Details

Journal
Acta Clinica Belgica
Published
2025-07-04
DOI
https://doi.org/10.1080/17843286.2025.2543336
Primary Topic
Syphilis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Evaluation of the AIX1000 automated rapid plasma reagin test in a tertiary academic medical center

Elizaveta Padalko, Taeyang Chin
1 links
Acta Clinica Belgica
Syphilis Diagnosis and Treatment
article

Evaluation of the AIX1000 automated rapid plasma reagin test in a tertiary academic medical center

Elizaveta Padalko, Taeyang Chin
article en

Abstract

The AIX1000 showed good concordance with manual RPR, particularly at lower titers, with reliable analytical performance and operational advantages. However, systematic titer underestimation compared to manual RPR, particularly in high-titer samples, may affect clinical interpretation if tests are transitioned. Clinicians should be informed of this discrepancy when transitioning platforms.

Acta Clinica BelgicaVol. 80(4)
Ghent University Hospital (BE)
Openalex Percentile: Top 75%
Syphilis Diagnosis and Treatment
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Evaluation of the AIX1000 automated rapid plasma reagin test in a tertiary academic medical center — Elizaveta Padalko, Taeyang Chin · Acta Clinica Belgica (2025) | TGRS Research Map | TGRS